Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TET genes: new players in DNA demethylation and important determinants for stemness.

Experimental hematology - 1 Mar 2011

Mohr Fabian, Döhner Konstanze, Buske Christian, Rawat Vijay P S

Abstract excerpt

Stem cells are defined as cells that have the ability to perpetuate themselves through self-renewal and to generate functional mature cells by differentiation. During each stage, coordinated gene expression is crucial to maintain the balance between self-renewal and differentiation. Disturbance of this accurately balanced system can lead to a variety of malignant disorders. In mammals, DNA cytosine-5 methylation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dioxygenases
Share to DNA-Binding Proteins
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Embryonic Stem Cells

Share to Epigenesis, Genetic

Share to Hematologic Neoplasms

Share to Mutation

Share to Proto-Oncogene Proteins

Source

Identifiers

PMID: 21168469
DOI: 10.1016/j.exphem.2010.12.004

Genes

TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TET genes: new players in DNA demethylation and important determinants for stemness.PMID 21168469Read ↗

TET2 as an epigenetic master regulator for normal and malignant hematopoiesis.Semantic proximity Read ↗

Epigenetic Function of TET Family, 5-Methylcytosine, and 5-Hydroxymethylcytosine in Hematologic MalignanciesSemantic proximity Read ↗

TET2: A cornerstone in normal and malignant hematopoiesis.Semantic proximity Read ↗

Epigenetic Modification of Cytosines in Hematopoietic Differentiation and Malignant TransformationSemantic proximity Read ↗

Roles and Regulations of TET Enzymes in Solid Tumors.Semantic proximity Read ↗

TET2 in Normal and Malignant Hematopoiesis.Semantic proximity Read ↗

TET proteins and 5-methylcytosine oxidation in hematological cancers.Semantic proximity Read ↗

Ten-Eleven-Translocation Genes in Cancer.Semantic proximity Read ↗

The TET2 interactors and their links to hematological malignancies.Semantic proximity Read ↗

TET1 is a tumor suppressor of hematopoietic malignancy.Semantic proximity Read ↗

5-Hydroxymethylcytosine: An epigenetic mark frequently deregulated in cancer.Semantic proximity Read ↗

TET2 Plays an Essential Role in Erythropoiesis by Regulating Lineage-Specific Genes via DNA Oxidative Demethylation in a Zebrafish ModelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.