Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The human induced pluripotent stem cell line CTGUi-002A was generated from a Perrault syndrome patient.

Stem cell research - 1 Apr 2026

Wu Shen-Lin, Li Yang, Dou Tonghai, Wang Wei, Zhan Jing-Qiong, Lv Ya-Feng

Abstract excerpt

We generated an induced pluripotent stem cell (iPSC) line, designated CTGUi002-A, from peripheral blood mononuclear cells (PBMCs) of a 9-year-old female with Perrault syndrome carrying biallelic TWNK mutations (c.811G>A and c.1163C>T), using Sendai virus-mediated delivery of OCT4, SOX2, KLF4, and c-MYC. The CTGUi002-A iPSC line retained the TWNK mutations and exhibited characteristic iPSC morphology, expressed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Karyotype
Share to Cell Differentiation
Share to Cell Line

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Induced Pluripotent Stem Cells

Share to Kruppel-Like Factor 4

Share to Leukocytes, Mononuclear

Share to Mutation

Source

Identifiers

PMID: 41722370
DOI: 10.1016/j.scr.2026.103929

Genes

TWNK
KLF4
MYC
SOX2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The human induced pluripotent stem cell line CTGUi-002A was generated from a Perrault syndrome patient.PMID 41722370Read ↗

Generation of the human induced pluripotent stem cell line PUMCi005-A from a patient with Perrault syndrome.Semantic proximity Read ↗

Generation of a human iPSC line (MPIi008-A) from a patient with Denys-Drash syndrome.Semantic proximity Read ↗

Generation of a human iPSC line (UUIGPi015-A) from a patient with Dravet syndrome and a 2.9 Mb deletion spanning SCN1A on chromosome 2.Semantic proximity Read ↗

Generation of an induced pluripotent stem cell line ATCi002-A from a two-year-old chinese boy with Keipert syndrome.Semantic proximity Read ↗

Generation of an induced pluripotent stem cell line (ZZUi022-A) from a paroxysmal kinesigenic dyskinesia individual carrying the PRRT2 gene mutation.Semantic proximity Read ↗

Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and DevelopmentSemantic proximity Read ↗

Generation of iPSC lines from peripheral blood mononuclear cells from 5 healthy adultsSemantic proximity Read ↗

Generation of one human induced pluripotent stem cell line (XACHi004-A) with heterozygous mutation of RYR2 gene from an atrial fibrillation patient.Semantic proximity Read ↗

Generation of four iPSC lines from four patients with Leigh syndrome carrying homoplasmic mutations m.8993T > G or m.8993T > C in the mitochondrial gene MT-ATP6.Semantic proximity Read ↗

Generation of an induced pluripotent stem cell (iPSC) line (THSJTUi001-A) from a Wilson's disease patient harboring a homozygous Arg778Leu mutation in ATP7B gene.Semantic proximity Read ↗

Recent Updates on Induced Pluripotent Stem Cells in Hematological DisordersSemantic proximity Read ↗

A new NHGRI Sample Repository for Human Genetic Research collection of induced pluripotent stem cell linesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.