Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Circular RNA circNIPBL regulates TP53-H179R mutations in NNK-induced bronchial epithelial carcinogenesis.

Environment international - 1 Aug 2024

Liu Yufei, Fang Shusen, Lin Tianshu, Chen Wei, Chen Yushan, Wang Ye, Xiao Xietian, Zheng Hengfa, Liu Lulu, Zhou Jiayu, Jiang Yan, Hua Qiuhan, Jiang Yiguo

Abstract excerpt

Exposure to environmental carcinogens is a significant contributor to cancer development, with genetic and epigenetic alterations playing pivotal roles in the carcinogenic process. However, the interplay between epigenetic regulation and genetic changes in carcinogenesis has yet to receive comprehensive attention. This study investigates the impact of continuous exposure to the tobacco-specific carcinogen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bronchi
Share to Carcinogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinogens

Share to Epithelial Cells

Share to Lung Neoplasms

Share to Nitrosamines

Share to RNA, Circular

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 38908277
DOI: 10.1016/j.envint.2024.108829

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Circular RNA circNIPBL regulates TP53-H179R mutations in NNK-induced bronchial epithelial carcinogenesis.PMID 38908277Read ↗

Circ_0001839 modulates the oncogenic MYCL rs1038259890 (p.G83S) mutation to promote B[a]P-induced malignant transformation in 16HBE cells.Semantic proximity Read ↗

SETBP1-R54P mutation promotes malignant transformation of cadmium-induced 16HBE cells by down-regulating circ_0007095 expression.Semantic proximity Read ↗

Human cancer genomes harbor the mutational signature of tobacco-specific nitrosamines NNN and NNKSemantic proximity Read ↗

Human cancer genomes harbor the mutational signature of tobacco-specific nitrosamines NNN and NNKSemantic proximity Read ↗

Defining mutational signatures of lung cancer-associated carcinogens through <i>in vitro</i> exposure of human airway epithelial cellsSemantic proximity Read ↗

CircPVT1 attenuates negative regulation of NRAS by let-7 and drives cancer cells towards oncogenicity.Semantic proximity Read ↗

Integrated analysis of circRNA-miRNA-mRNA network reveals potential prognostic biomarkers for radiotherapies with X-rays and carbon ions in non-small cell lung cancerSemantic proximity Read ↗

Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers.Semantic proximity Read ↗

Incense-burning smoke ingredient Auramine enhances lincRNA-p21 expression for chemosensitization in p53-mutated non-small cell lung cancer.Semantic proximity Read ↗

Cadmium-induced POLN mutations promote m6A-dependent circ_FANCA degradation via endoribonucleolytic cleavage, triggering TCA cycle activation and oncogenic transformation.Semantic proximity Read ↗

Roles of translesion synthesis DNA polymerases in the potent mutagenicity of tobacco-specific nitrosamine-derived O2-alkylthymidines in human cells.Semantic proximity Read ↗

Nicotine Promotes WRL68 Cells Proliferation Due to the Mutant p53 Gain-of-Function by Activating CDK6-p53-RS-PIN1-STAT1 Signaling Pathway.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.