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Integrated analysis of circRNA-miRNA-mRNA network reveals potential prognostic biomarkers for radiotherapies with X-rays and carbon ions in non-small cell lung cancer

1 Nov 2020

Abstract excerpt

BACKGROUND: This work was aimed at exploring the regulatory network of non-coding RNA (ncRNA) especially circular RNA (circRNA) and microRNA (miRNA), in the sensitivity of non-small cell lung cancer (NSCLC) cells to low linear energy transfer (LET) X-ray and high-LET carbon ion irradiations. METHODS: The radioresistant NSCLC cell line A549-R11 was obtained from its parental cell line A549 through irradiation with...

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PMID: 33313118
DOI: 10.21037/atm-20-2002

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