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Article

The influence of UGT2B7 genotype on valproic acid pharmacokinetics in Chinese epilepsy patients.

Epilepsy research - 1 Aug 2015

Sun Yin-xiang, Zhuo Wen-yan, Lin Hong, Peng Zheng-ke, Wang Hua-ming, Huang Hao-wu, Luo Yu-hong, Tang Fa-qing

Abstract excerpt

PURPOSE: The aim of this study was to investigate the distribution and frequency of genetic polymorphisms in uridine diphosphate glucuronosyltransferase-2B7 (UGT2B7) in epilepsy patients and to evaluate the effect of these on the metabolism of valproic acid (VPA). METHODS: Single nucleotide polymorphisms in UGT2B7 were investigated in 102 epilepsy patients using DNA sequencing and polymerase chain...

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Identifiers

PMID: 26088889
DOI: 10.1016/j.eplepsyres.2015.04.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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