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Diagnostic Yield of APOL1 p.N264K Variant Screening in Daily Practice

4 Apr 2024

Abstract excerpt

Observational and case-control studies in large American cohorts of individuals of African ancestry with available genetic information have demonstrated a strong protective effect of the p.N264K variant of APOL1 on the risk of chronic kidney disease (CKD), focal segmental glomerulosclerosis (FSGS), and end-stage kidney disease 1,2. This variant is only effective in the presence of the high-risk, African, G2...

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PMID: 38899219
DOI: 10.1016/j.ekir.2024.04.008

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