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Article

APOL1 kidney risk alleles: population genetics and disease associations.

Advances in chronic kidney disease - 1 Sept 2014

Limou Sophie, Nelson George W, Kopp Jeffrey B, Winkler Cheryl A

Abstract excerpt

APOL1 kidney disease is a unique case in the field of the genetics of common disease: 2 variants (termed G1 and G2) with high population frequency have been repeatedly associated with nondiabetic CKDs, with very strong effect size (odds ratios 3-29) in populations of sub-Saharan African descent. This review provides an update on the spectrum of APOL1 kidney disease and on the worldwide distribution of these...

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Source

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Identifiers

PMID: 25168832
DOI: 10.1053/j.ackd.2014.06.005
PMCID: PMC4157456

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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