Article
SNP-slice resolves mixed infections: simultaneously unveiling strain haplotypes and linking them to hosts.
Bioinformatics (Oxford, England) - 3 Jun 2024
Ju Nianqiao, Liu Jiawei, He Qixin
Abstract excerpt
MOTIVATION: Multi-strain infection is a common yet under-investigated phenomenon of many pathogens. Currently, biologists analyzing SNP information sometimes have to discard mixed infection samples as many downstream analyses require monogenomic inputs. Such a protocol impedes our understanding of the underlying genetic diversity, co-infection patterns, and genomic relatedness of pathogens. A scalable tool to...
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