Article

Coalescent inference using serially sampled, high-throughput sequencing data from intra-host HIV infection

2015-06-07

Abstract excerpt

<h4>ABSTRACT</h4> Human immunodeficiency virus (HIV) is a rapidly evolving pathogen that causes chronic infections, so genetic diversity within a single infection can be very high. High-throughput “deep” sequencing can now measure this diversity in unprecedented detail, particularly since it can be performed at different timepoints during an infection, and this offers a potentially powerful way to infer the evolu...

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Literature Corpus work: 54b2dda8-e250-53cb-9d55-d22120b4225e
DOI: 10.1101/020552

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