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A new method for detecting mixed <i>Mycobacterium tuberculosis</i> infection and reconstructing constituent strains provides insights into transmission

2024-04-29

Abstract excerpt

<h4>Background</h4> Mixed infection with multiple strains of the same pathogen in a single host can present clinical and analytical challenges. Whole genome sequence (WGS) data can identify signals of multiple strains in samples, though the precision of previous methods can be improved. Here, we present MixInfect2, a new tool to accurately detect mixed samples from Mycobacterium tuberculosis WGS data. We then e...

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Literature Corpus work
30f197eb-d761-5d7b-8aed-5b562035bc17
DOI
10.1101/2024.04.26.591283
Open publication

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A new method for detecting mixed <i>Mycobacterium tuberculosis</i> infection and reconstructing constituent strains provides insights into transmissionDOI 10.1101/2024.04.26.591283
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