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Article

THE REAL McCOIL: A method for the concurrent estimation of the complexity of infection and SNP allele frequency for malaria parasites.

PLoS computational biology - 1 Jan 2017

Chang Hsiao-Han, Worby Colin J, Yeka Adoke, Nankabirwa Joaniter, Kamya Moses R, Staedke Sarah G, Dorsey Grant, Murphy Maxwell, Neafsey Daniel E, Jeffreys Anna E, Hubbart Christina, Rockett Kirk A, Amato Roberto, Kwiatkowski Dominic P, Buckee Caroline O, Greenhouse Bryan

Abstract excerpt

As many malaria-endemic countries move towards elimination of Plasmodium falciparum, the most virulent human malaria parasite, effective tools for monitoring malaria epidemiology are urgent priorities. P. falciparum population genetic approaches offer promising tools for understanding transmission and spread of the disease, but a high prevalence of multi-clone or polygenomic infections can render estimation of...

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Identifiers

PMID: 28125584
DOI: 10.1371/journal.pcbi.1005348
PMCID: PMC5300274

Genes

COIL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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