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Article

Normotensive metabolic syndrome in Transient Receptor Potential Canonical Channel type 1 Trpc1-/- mice.

Biology open - 15 Jul 2024

Atkins Richard Matthew, Pantalia Meghan, Skaggs Christopher, Lau Alexander Ku, Mahmood Muhammad Bilal, Anwar Muhammad Mubeen, Barron Lindsay, Eby Bonnie, Khan Usman, Tsiokas Leo, Lau Kai

Abstract excerpt

Metabolic syndrome has become a global epidemic, affecting all developed countries and communities with growing economies. Worldwide, increasing efforts have been directed at curbing this growing problem. Mice deleted of the gene encoding Type 1 Transient Receptor Potential Canonical Channel (Trpc1) were found to weigh heavier than controls. They had fasting hyperglycemia and impaired glucose tolerance compared...

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Identifiers

PMID: 38885005
DOI: 10.1242/bio.060280
PMCID: PMC11317093

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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