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Article

KDM4B mutations in human cancers.

Mutation research - 1 Jan 2000

Bush Wesley, Bosart Korey, Bouley Renee A, Petreaca Ruben C

Abstract excerpt

Homologous recombination (HR) is essential for repair of DNA double-strand breaks (DSBs) and restart of stalled or collapsed replication forks. Most cancers are characterized by mutations in components of the DSB repair pathways. Redundant DSB repair pathways exist in eukaryotes from yeast to humans and recent evidence has shown that complete loss of HR function appears to be lethal. Recent evidence has also...

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Identifiers

PMID: 38878505
DOI: 10.1016/j.mrfmmm.2024.111866
PMCID: PMC11585459

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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