Article
KRAS, NRAS and BRAF Mutational Profile of Colorectal Cancer in a Series of Moroccan Patients.
Cancer control : journal of the Moffitt Cancer Center - 1 Jan 2000
El Zaitouni Sara, Laraqui Abdelilah, Ghaouti Meriem, Benzekri Asmae, Kettani Fouad, Bajjou Tahar, Sekhsokh Yassine, Benmokhtar Soukaina, Jafari Meryem, Baba Walid, Oukabli Mohamed, El Annaz Hicham, Abi Rachid, Tagajdid Mohamed Rida, El Kochri Safae, Lahlou Idriss Amine, Ameziane El Hassani Rabii, Ennibi Khalid
Abstract excerpt
OBJECTIVES: The present study aimed to evaluate the frequencies of KRAS, NRAS, and BRAF mutations and their possible associations with clinicopathological features in 249 Moroccan patients with colorectal cancer (CRC). METHODS: A retrospective investigation of a cohort of formalin-fixed paraffin-embedded tissues of 249 patients with CRC was screened for KRAS/NRAS/BRAF mutations using Idylla™ technology and...
Topics
- Humans
- Proto-Oncogene Proteins B-raf
- Colorectal Neoplasms
- Male
- Female
- Proto-Oncogene Proteins p21(ras)
- Membrane Proteins
- Middle Aged
- GTP Phosphohydrolases
