Prevalence and patterns of mutations in RAS/RAF/MEK/ERK/MAPK signaling pathway in colorectal cancer in North Africa.

doi:10.1186/s12885-022-10235-w

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Prevalence and patterns of mutations in RAS/RAF/MEK/ERK/MAPK signaling pathway in colorectal cancer in North Africa.

BMC cancer - 7 Nov 2022

Jafari Meryem, Laraqui Abdelilah, Baba Walid, Benmokhtar Soukaina, Zaitouni Sara El, Ali Abdelmounaim Ait, Bounaim Ahmed, Moujahid Mountassir, Tanz Rachid, Mahfoud Tarik, Sbitti Yassir, Annaz Hicham El, Abi Rachid, Tagajdid Mohamed Rida, Kochri Safae El, Lahlou Idriss Amine, Hsaini Houda El, Belayachi Lamiae, Benjouad Abdelaziz, Ichou Mohammed, En-Nya Amina, Ennibi Khalid

Abstract excerpt

BACKGROUND: Our review discuss (i) the findings from analyzed data that have examined KRAS, NRAS and BRAF mutations in patients with colorectal cancer (CRC) in North Africa and to compare its prevalence with that shown in other populations and (ii) the possible role of dietary and lifestyle factors with CRC risk. METHODS: Using electronic databases, a systematic literature search was performed for the...

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PMID: 36344948
DOI: 10.1186/s12885-022-10235-w
PMCID: PMC9639273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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