Distribution of KRAS and BRAF mutations in Moroccan patients with advanced colorectal cancer.

doi:10.1016/j.patbio.2013.05.004

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Article

Distribution of KRAS and BRAF mutations in Moroccan patients with advanced colorectal cancer.

Pathologie-biologie - 1 Dec 2013

Marchoudi N, Amrani Hassani Joutei H, Jouali F, Fekkak J, Rhaissi H

Abstract excerpt

Targeted therapies have an increasing importance in digestive oncology. To our knowledge, we are the first to report the distribution of KRAS and BRAF mutations in Moroccan patients with advanced colorectal cancer (CRC) in order to introduce targeted therapy in the arsenal of therapeutic modalities for management of this cancer in Morocco. In this study, 92 samples obtained from patients with CRC were tested for...

Topics

Adult
Aged
Aged, 80 and over
Colorectal Neoplasms
Disease Progression
Drug Resistance, Neoplasm
ErbB Receptors
Female
Gene Frequency
Humans
Male
Middle Aged
Morocco
Mutation
Polymorphism, Single Nucleotide
Protein Kinase Inhibitors
Proto-Oncogene Proteins
Proto-Oncogene Proteins B-raf

Source

Open in PubMed

Identifiers

PMID: 23849768
DOI: 10.1016/j.patbio.2013.05.004

Genes

KRAS
BRAF
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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