Prevalence of colorectal cancer biomarkers and their impact on clinical outcomes in Riyadh, Saudi Arabia.

doi:10.1371/journal.pone.0249590

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Article

Prevalence of colorectal cancer biomarkers and their impact on clinical outcomes in Riyadh, Saudi Arabia.

PloS one - 1 Jan 2021

Alharbi Amjad, Bin Dokhi Haifa, Almuhaini Ghadir, Alomran Futoon, Masuadi Emad, Alomran Nouf

Abstract excerpt

OBJECTIVES: KRAS, NRAS, and BRAF mutations are commonly present in colorectal cancer (CRC). We estimated the frequency of KRAS, NRAS, and BRAF mutations and assessed their impact on survival and other clinical variables among Saudi patients. DESIGN: Retrospective cohort study design. SETTINGS: On...

Topics

Aged
Biomarkers, Tumor
Chi-Square Distribution
Colorectal Neoplasms
Female
GTP Phosphohydrolases
Humans
Male
Membrane Proteins
Middle Aged
Mutation
Prevalence
Proto-Oncogene Proteins B-raf
Proto-Oncogene Proteins p21(ras)
Retrospective Studies
Saudi Arabia

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Identifiers

PMID: 33979337
DOI: 10.1371/journal.pone.0249590
PMCID: PMC8116043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-33979337-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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