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Article

Clinicopathological characteristics and mutational profile of KRAS and NRAS in Tunisian patients with sporadic colorectal cancer

Turkish journal of medical sciences - 26 Feb 2021

Ounissi Donia, Weslati Marwa, Boughriba Rahma, Hazgui Meriam, Bouraoui Saadia

Abstract excerpt

Background/aim: Colorectal cancer (CRC) is a major public health problem worldwide and in Tunisia due to its increasing rate of incidence. KRAS and NRAS mutations have become a pivotal part of CRC diagnosis, given their association to treatment resistance with antiepidermal growth factor receptor (EGFR) monoclonal antibodies. In this study, we aimed to screen for mutations in KRAS and NRAS genes in Tunisian...

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Source

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Identifiers

PMID: 32892548
DOI: 10.3906/sag-2003-42
PMCID: PMC7991861

Genes

KRAS
NRAS
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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