Article
Mutation status and prognostic value of KRAS and NRAS mutations in Moroccan colon cancer patients: A first report.
PloS one - 1 Jan 2021
El Agy Fatima, El Bardai Sanae, El Otmani Ihsane, Benbrahim Zineb, Karim Ibn Majdoub Hassani, Mazaz Khalid, Benjelloun El Bachir, Ousadden Abdelmalek, El Abkari Mohammed, Ibrahimi Sidi Adil, Chbani Laila
Abstract excerpt
This study aimed to estimate the incidence of KRAS, NRAS, and BRAF mutations in the Moroccan population, and investigate the associations of KRAS and NRAS gene mutations with clinicopathological characteristics and their prognosis value. To achieve these objectives, we reviewed medical and pathology reports for 210 patients. RAS testing was investigated by Sanger sequencing and Pyrosequencing technology. BRAF...
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