Article

A3D Database: Structure-based Protein Aggregation Predictions for the Human Proteome

2021-11-19

Abstract excerpt

<h4>Motivation</h4> Protein aggregation is associated with highly debilitating human disorders and constitutes a major bottleneck for producing therapeutic proteins. Our knowledge of the human protein structures repertoire has dramatically increased with the recent development of the AlphaFold (AF) deep-learning method. This structural information can be used to understand better protein aggregation properties an...

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Literature Corpus work: 6dc84940-7b24-5f68-9e0c-09be047ff3ad
DOI: 10.1101/2021.11.17.468872

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