Article

In Silico Predictive Homology Modeling of PKHD-1 Protein: A Comparative Study among Three Different Species

2023-11-28

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> The PKHD-1 (Polycystic Kidney and Hepatic Disease-1) gene encodes a crucial protein vital for renal and hepatic functions. Mutations in PKHD-1 result in Autosomal Recessive Polycystic Kidney Disease (ARPKD), a severe disorder in early infancy. Despite its significance, the structural information on PKHD-1 remains limited, with few low-resolution structures ac...

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Literature Corpus work: cac2f20d-1872-5742-8f29-aec2a359d899
DOI: 10.21203/rs.3.rs-3506214/v3

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