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Polygenic Risk Score Modifies the Association of HbA1c With Hearing Loss in Middle-Aged and Older Chinese Individuals: The Dongfeng-Tongji Cohort.

Diabetes care - 1 Jul 2024

He Yaling, Wang Zhichao, Zhang Haiqing, Lai Xuefeng, Liu Miao, Yang Liangle, Zheng Yiquan, He Meian, Kong Weijia, Zhang Xiaomin

Abstract excerpt

OBJECTIVE: Evidence regarding the modifying effect of the polygenic risk score (PRS) on the associations between glycemic traits and hearing loss (HL) was lacking. We aimed to examine whether these associations can be influenced by genetic susceptibility. RESEARCH DESIGN AND METHODS: This cross-sectional study included 13,275 participants aged 64.9 years from the Dongfeng-Tongji cohort. HL was defined according...

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Identifiers

PMID: 38728232
DOI: 10.2337/dc23-2341
PMCID: PMC11208759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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