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Early‐onset type 2 diabetes is associated with genetic variants of β‐cell function in the Chinese Han population

29 Aug 2019

Abstract excerpt

Abstract Aims To investigate the genetic factors contributing to early‐onset type 2 diabetes (EOD) in the Chinese Hans populations. Materials and methods For 2734 newly diagnosed type 2 diabetes patients and 4041 normal glycemic controls, 25 single nucleotide polymorphisms from 24 genomic loci linked to diabetes were successfully genotyped. Three genetic risk scores (GRSs) were constructed, including the weighted...

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PMID: 31465628
DOI: 10.1002/dmrr.3214

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