Article
Impact of the trans-ancestry polygenic risk score on type 2 diabetes risk, onset age and progression among population in Taiwan.
American journal of physiology. Endocrinology and metabolism - 1 May 2024
Wang Shi-Heng, Huang Yu-Chuen, Cheng Chun-Wen, Chang Ya-Wen, Liao Wen-Ling
Abstract excerpt
Type 2 diabetes (T2D) prevalence in adults at a younger age has increased but the disease status may go unnoticed. This study aimed to determine whether the onset age and subsequent diabetic complications can be attributed to the polygenic architecture of T2D in the Taiwan Han population. A total of 9,627 cases with T2D and 85,606 controls from the Taiwan Biobank were enrolled. Three diabetic polygenic risk...
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