Article
Possible Modifying Effect of Hemoglobin A1c on Genetic Susceptibility to Severe Diabetic Retinopathy in Patients With Type 2 Diabetes.
Investigative ophthalmology & visual science - 3 Aug 2020
Ng Kelvin K K, Cheung Chloe Y Y, Lee Chi-Ho, Fong Carol H Y, Kwok Kelvin H M, Li Kenneth K W, Gangwani Rita A, Wong Ian Y H, Woo Yu-Cho, Chow Wing-Sun, Yuen Michele M A, Wong Rachel L C, Xu Aimin, Wong David S H, Sham Pak-Chung, Lam Karen S L
Abstract excerpt
Purpose: Glycemic control has been recognized as an important modifiable risk factor for diabetic retinopathy (DR). Whether hemoglobin A1c (HbA1c), as an indicator of glycemic control, could modify the genetic susceptibility to severe DR remains to be investigated. This study aimed to investigate whether HbA1c could modulate the genetic susceptibility to severe DR in Chinese patients with type 2 diabetes....
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