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Article

Polygenic risk score analysis of noise-induced hearing loss: An integrated cross-sectional and longitudinal study.

Hearing research - 1 Sept 2026

Li Jiayu, Yu Xiao, Shen Wenxin, Wang Ying, Wang Jian, Wang Jiping, Li Shiyuan, Ma Xinrong, Guo Junjie, Dong Hongyu, Ma Yiming, Zhang Hongfu, Cai Jingjing, Zhang Ren, Yang Jingwen, Zan Hongyuan, Salvi Richard, Shi Haibo, Hao Xingjie, Wang Hui, Yin Shankai

Abstract excerpt

BACKGROUND: Substantial variability in susceptibility to noise-induced hearing loss (NIHL) with comparable noise exposures suggests a genetic contribution, but population-based evidence remains limited. This study evaluated whether a polygenic risk score (PRS), summarizing the effect of genetic variants, was associated with NIHL susceptibility. METHODS: Participants were recruited from an ongoing Occupational...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 42361732
DOI: 10.1016/j.heares.2026.109710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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