Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiple polygenic risk scores can improve the prediction of systemic lupus erythematosus in Taiwan.

Lupus science & medicine - 9 May 2024

Chen Yu-Chia, Liu Ting-Yuan, Lu Hsing-Fang, Huang Chung-Ming, Liao Chi-Chou, Tsai Fuu-Jen

Abstract excerpt

OBJECTIVE: To identify new genetic variants associated with SLE in Taiwan and establish polygenic risk score (PRS) models to improve the early diagnostic accuracy of SLE. METHODS: The study enrolled 2429 patients with SLE and 48 580 controls from China Medical University Hospital in Taiwan. A genome-wide association study (GWAS) and PRS analyses of SLE and other three SLE markers, namely ANA, anti-double-stranded...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Antinuclear
Share to Genetic Risk Score

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Haplotypes

Share to HLA-DQ alpha-Chains

Share to HLA-DQ beta-Chains

Share to Lupus Erythematosus, Systemic

Share to Taiwan

Source

Open in PubMed Open full text

Identifiers

PMID: 38724181
DOI: 10.1136/lupus-2023-001035
PMCID: PMC11086529

Genes

EGLN3
RCC1L

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple polygenic risk scores can improve the prediction of systemic lupus erythematosus in Taiwan.PMID 38724181Read ↗

Polygenic Risk Score Predicts Earlier-Onset Adult Systemic Lupus Erythematosus and First-Year Renal Diseases in a Taiwanese Cohort.Semantic proximity Read ↗

Higher Genetic Risk Loads Confer More Diverse Manifestations and Higher Risk of Lupus Nephritis in Systemic Lupus Erythematosus.Semantic proximity Read ↗

Systemic lupus erythematosus: a genetic epidemiology study of 695 patients from China.Semantic proximity Read ↗

Genome-wide assessment of genetic risk for systemic lupus erythematosus and disease severity.Semantic proximity Read ↗

Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity that may underly population disparities in this diseaseSemantic proximity Read ↗

Genome-wide assessment of genetic risk for systemic lupus erythematosus and disease severitySemantic proximity Read ↗

Confirmation of five novel susceptibility loci for systemic lupus erythematosus (SLE) and integrated network analysis of 82 SLE susceptibility loci.Semantic proximity Read ↗

Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.Semantic proximity Read ↗

Genetics of Systemic Lupus ErythematosusSemantic proximity Read ↗

Characterization of primary Sjögren's syndrome in the Taiwan Han population through a genome-wide association study and polygenic risk score analysis.Semantic proximity Read ↗

Identification of Key Genes in Systemic Lupus Erythematosus through integrated bioinformaticsSemantic proximity Read ↗

Genetic susceptibility to SLE: recent progress from GWAS.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.