Article
Genetic susceptibility to SLE: recent progress from GWAS.
Journal of autoimmunity - 1 Mar 2013
Cui Yong, Sheng Yujun, Zhang Xuejun
Abstract excerpt
Systemic lupus erythematosus (SLE) is a prototype autoimmune disease with a strong genetic component, characterized by hyperactive T and B cells, autoantibody production, immune complex deposition and multi-organ damage. It affects predominantly women of child-bearing age and has population differences in both disease prevalence and severity. Genetic factors are known to play key roles in the disease through the...
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