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Article

Implication of system xc- in neuroinflammation during the onset and maintenance of neuropathic pain.

Journal of neuroinflammation - 7 May 2024

Beckers Pauline, Belo Do Nascimento Inês, Charlier Mathilde, Desmet Nathalie, Massie Ann, Hermans Emmanuel

Abstract excerpt

BACKGROUND: Despite the high prevalence of neuropathic pain, treating this neurological disease remains challenging, given the limited efficacy and numerous side effects associated with current therapies. The complexity in patient management is largely attributed to an incomplete understanding of the underlying pathological mechanisms. Central sensitization, that refers to the adaptation of the central nervous...

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Identifiers

PMID: 38715127
DOI: 10.1186/s12974-024-03112-9
PMCID: PMC11077843

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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