Article

Translational control in the spinal cord regulates gene expression and pain hypersensitivity in the chronic phase of neuropathic pain

2024-06-28

Abstract excerpt

<h4>Summary</h4> Sensitization of spinal nociceptive circuits plays a crucial role in neuropathic pain. This sensitization depends on new gene expression that is primarily regulated via transcriptional and translational control mechanisms. The relative roles of these mechanisms in regulating gene expression in the clinically relevant chronic phase of neuropathic pain are not well understood. Here, we show that ch...

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Literature Corpus work: 97ac7d3f-3de1-5c3e-a379-8210d8d8df4c
DOI: 10.1101/2024.06.24.600539

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