Article

Sexual dimorphism in a neuronal mechanism of spinal hyperexcitability across rodent and human models of pathological pain

2021-06-16

Abstract excerpt

The prevalence and severity of many chronic pain syndromes differ across sex, and recent studies have identified differences in immune signalling within spinal nociceptive circuits as a potential mediator. Although it has been proposed that sex-specific pain mechanisms converge once they reach neurons within the superficial dorsal horn (SDH), direct investigations using rodent and human preclinical pain models hav...

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Literature Corpus work: 9f6d2fa4-4fe6-5b00-99de-4965bf23bdcf
DOI: 10.1101/2021.06.15.447407

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