Article

Functional contribution of astrocytic Kir4.1 channels to spasticity after spinal cord injury

2024-10-12

Abstract excerpt

<h4>Summary</h4> Spasticity, a prevalent motor issue characterized by network hyperexcitability, causes pain and discomfort, with existing treatments offering limited relief. While past research has focused on neuronal factors, the role of astrocytes in spasticity has been overlooked. This study explores the potential of restoring astrocytic potassium (K + ) uptake to reduce spasticity following SCI. Astrocytes...

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Literature Corpus work: e024b2c3-01a9-563a-a067-6f1f8a9f8ff2
DOI: 10.1101/2024.10.11.617793

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