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Article

A polygenetic risk score combined with environmental factors better predict susceptibility to hepatocellular carcinoma in Chinese population.

Cancer medicine - 1 May 2024

Zou Yuanlin, Zhu Jicun, Song Caijuan, Li Tiandong, Wang Keyan, Shi Jianxiang, Ye Hua, Wang Peng

Abstract excerpt

AIMS: This study aimed to investigate environmental factors and genetic variant loci associated with hepatocellular carcinoma (HCC) in Chinese population and construct a weighted genetic risk score (wGRS) and polygenic risk score (PRS). METHODS: A case-control study was applied to confirm the single nucleotide polymorphisms (SNPs) and environmental variables linked to HCC in the Chinese population, which had been...

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Identifiers

PMID: 38698686
DOI: 10.1002/cam4.7230
PMCID: PMC11066500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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