Article
Estimation of heritability for nine common cancers using data from genome-wide association studies in Chinese population.
International journal of cancer - 15 Jan 2017
Dai Juncheng, Shen Wei, Wen Wanqing, Chang Jiang, Wang Tongmin, Chen Haitao, Jin Guangfu, Ma Hongxia, Wu Chen, Li Lian, Song Fengju, Zeng YiXin, Jiang Yue, Chen Jiaping, Wang Cheng, Zhu Meng, Zhou Wen, Du Jiangbo, Xiang Yongbing, Shu Xiao-Ou, Hu Zhibin, Zhou Weiping, Chen Kexin, Xu Jianfeng, Jia Weihua, Lin Dongxin, Zheng Wei, Shen Hongbing
Abstract excerpt
The familial aggregation indicated the inheritance of cancer risk. Recent genome-wide association studies (GWASs) have identified a number of common single-nucleotide polymorphisms (SNPs). Following heritability analyses have shown that SNPs could explain a moderate amount of variance for different cancer phenotypes among Caucasians. However, little information was available in Chinese population. We performed a...
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