Article
Genetic risk and gastric cancer: polygenic risk scores in population-based case-control study.
Expert review of molecular diagnostics - 1 Jun 2023
Duan Fujiao, Liu Ling, Chen Xiaolin, Yang Qian, Wang Yiran, Zhang Yaodong, Wang Kaijuan
Abstract excerpt
OBJECTIVE: This study aimed to screen and identify common variants and long noncoding RNA (lncRNA) single nucleotide polymorphisms (SNPs) associated with gastric cancer risk, and construct prediction models based on polygenic risk score (PRS). METHODS: The risk factors associated with gastric cancer were screened following meta-analysis and bioinformatics, verified by population-based case-control study. We...
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