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Article

Autocorrelation analysis of a phenotypic screen reveals hidden drug activity.

Scientific reports - 2 May 2024

Dubach Richard A, Dubach J Matthew

Abstract excerpt

Phenotype based screening is a powerful tool to evaluate cellular drug response. Through high content fluorescence imaging of simple fluorescent labels and complex image analysis phenotypic measurements can identify subtle compound-induced cellular changes unique to compound mechanisms of action (MoA). Recently, a screen of 1008 compounds in three cell lines was reported where analysis detected changes in...

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Identifiers

PMID: 38698021
DOI: 10.1038/s41598-024-60654-x
PMCID: PMC11066105

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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