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Article

Experimental evolution for the recovery of growth loss due to genome reduction.

eLife - 1 May 2024

Hitomi Kenya, Ishii Yoichiro, Ying Bei-Wen

Abstract excerpt

As the genome encodes the information crucial for cell growth, a sizeable genomic deficiency often causes a significant decrease in growth fitness. Whether and how the decreased growth fitness caused by genome reduction could be compensated by evolution was investigated here. Experimental evolution with an Escherichia coli strain carrying a reduced genome was conducted in multiple lineages for approximately 1000...

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Identifiers

PMID: 38690805
DOI: 10.7554/eLife.93520
PMCID: PMC11062635

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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