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Article

Coordinated Changes in Mutation and Growth Rates Induced by Genome Reduction.

mBio - 5 Jul 2017

Nishimura Issei, Kurokawa Masaomi, Liu Liu, Ying Bei-Wen

Abstract excerpt

Genome size is determined during evolution, but it can also be altered by genetic engineering in laboratories. The systematic characterization of reduced genomes provides valuable insights into the cellular properties that are quantitatively described by the global parameters related to the dynamics of growth and mutation. In the present study, we analyzed a small collection of W3110 Escherichia coli derivatives...

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Identifiers

PMID: 28679744
DOI: 10.1128/mBio.00676-17
PMCID: PMC5573674

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