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Transcriptional Potential Determines the Adaptability of Escherichia coli Strains with Different Fitness Backgrounds.

Microbiology spectrum - 21 Dec 2022

Kim Kitae, Kwon Soon-Kyeong, Kim Pil, Kim Jihyun F

Abstract excerpt

Adaptation through the fitness landscape may be influenced by the gene pool or expression network. However, genetic factors that determine the contribution of beneficial mutations during adaptive evolution are poorly understood. In this study, we experimentally evolved wild-type Escherichia coli K-12 MG1655 and its isogenic derivative that has two additional replication origins and shows higher background...

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Identifiers

PMID: 36445144
DOI: 10.1128/spectrum.02528-22
PMCID: PMC9769844

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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