Article
Prediction of Cross-resistance and Collateral Sensitivity by Gene Expression profiles and Genomic Mutations.
Scientific reports - 25 Oct 2017
Horinouchi Takaaki, Suzuki Shingo, Kotani Hazuki, Tanabe Kumi, Sakata Natsue, Shimizu Hiroshi, Furusawa Chikara
Abstract excerpt
In adaptive evolution, an increase in fitness to an environment is frequently accompanied by changes in fitness to other environmental conditions, called cross-resistance and sensitivity. Although the networks between fitness changes affect the course of evolution substantially, the mechanisms underlying such fitness changes are yet to be fully elucidated. Herein, we performed high-throughput laboratory evolution...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.