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Article

Hippocampal transcriptome-wide association study and neurobiological pathway analysis for Alzheimer's disease.

PLoS genetics - 1 Feb 2021

Liu Nana, Xu Jiayuan, Liu Huaigui, Zhang Shijie, Li Miaoxin, Zhou Yao, Qin Wen, Li Mulin Jun, Yu Chunshui

Abstract excerpt

Genome-wide association studies (GWASs) have identified multiple susceptibility loci for Alzheimer's disease (AD), which is characterized by early and progressive damage to the hippocampus. However, the association of hippocampal gene expression with AD and the underlying neurobiological pathways remain largely unknown. Based on the genomic and transcriptomic data of 111 hippocampal samples and the summary data...

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Identifiers

PMID: 33630843
DOI: 10.1371/journal.pgen.1009363
PMCID: PMC7906391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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