Article
GBA moderates cognitive reserve's effect on cognitive function in patients with Parkinson's disease.
Journal of neurology - 1 Jul 2024
Chang Chia-Wen, Tan Chun-Hsiang, Hong Wei-Pin, Yu Rwei-Ling
Abstract excerpt
BACKGROUND: Cognitive reserve (CR) involves an individual's ability to maintain cognitive vitality over their lifespan. Glucocerebrosidase (GBA) gene mutations contribute to additional effects on cognitive function in Parkinson's disease (PD) patients, but the interplay between GBA mutations and CR remains unclear. We investigated the interactions among CR, GBA, and diseases, aiming to examine whether the CR...
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