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Article

Cognitive and motor functioning in elderly glucocerebrosidase mutation carriers.

Neurobiology of aging - 1 Oct 2017

Moran Eileen E, Wang Cuiling, Katz Mindy, Ozelius Laurie, Schwartz Alison, Pavlovic Jelena, Ortega Roberto A, Lipton Richard B, Zimmerman Molly E, Saunders-Pullman Rachel

Abstract excerpt

Mutations in the glucocerebrosidase (GBA) gene are a strong genetic risk factor for the development of Parkinson's disease and dementia with Lewy Bodies. However the penetrance of GBA mutations is low for these diseases in heterozygous carriers. The aim of this study was to examine the relationship between mutation status and cognitive and motor functioning in a sample of community-dwelling older adults. Using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28728889
DOI: 10.1016/j.neurobiolaging.2017.06.010
PMCID: PMC5647652

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