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Article

Glucocerebrosidase Mutations and Motor Reserve in Parkinson's Disease.

Journal of Parkinson's disease - 1 Jan 2021

Chung Seok Jong, Lee Phil Hyu, Sohn Young H, Kim Yun Joong

Abstract excerpt

BACKGROUND: The concept of motor reserve explains the individual differences in motor deficits despite similar degrees of nigrostriatal dopamine depletion in Parkinson's disease (PD). OBJECTIVE: To investigate glucocerebrosidase (GBA) variants as potential determinants of motor reserve for exploratory purposes. METHODS: A total of 408 patients with drug-naïve PD were enrolled from the Parkinson's Progression...

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PMID: 34459414
DOI: 10.3233/JPD-212758

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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