Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Meta-analysis of breast cancer risk for individuals with PALB2 pathogenic variants.

Genetic epidemiology - 1 Dec 2024

Ruberu Thanthirige L M, Braun Danielle, Parmigiani Giovanni, Biswas Swati

Abstract excerpt

Multigene panel testing now allows efficient testing of many cancer susceptibility genes leading to a larger number of mutation carriers being identified. They need to be counseled about their cancer risk conferred by the specific gene mutation. An important cancer susceptibility gene is PALB2. Multiple studies reported risk estimates for breast cancer (BC) conferred by pathogenic variants in PALB2. Due to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bayes Theorem
Share to Breast Neoplasms
Share to Fanconi Anemia Complementation Group N Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to PALB2 gene

Share to Genetic Predisposition to Disease

Share to Mutation

Share to Odds Ratio

Share to Risk Factors

Source

Identifiers

PMID: 38654400
DOI: 10.1002/gepi.22561

Genes

PALB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Meta-analysis of breast cancer risk for individuals with PALB2 pathogenic variants.PMID 38654400Read ↗

Meta-Analysis of Breast Cancer Risk for Individuals with PALB2 Pathogenic VariantsSemantic proximity Read ↗

Common variants in the PALB2 gene confer susceptibility to breast cancer: a meta-analysis.Semantic proximity Read ↗

Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families.Semantic proximity Read ↗

PALB2 and the risks for cancer: implications for clinical care.Semantic proximity Read ↗

Management of individuals with germline variants in PALB2: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG).Semantic proximity Read ↗

Clinical outcomes in women with breast cancer and a PALB2 mutation: a prospective cohort analysis.Semantic proximity Read ↗

Adjusting for Ascertainment Bias in Meta-Analysis of Penetrance for Cancer Risk.Semantic proximity Read ↗

PALB2 mutations in breast cancer patients from a multi-ethnic region in northwest China.Semantic proximity Read ↗

Spectrum and characteristics of germline PALB2 pathogenic variants in 1556 early-onset breast cancer patients in China.Semantic proximity Read ↗

Spectrum of PALB2 germline mutations and characteristics of PALB2-related breast cancer: Screening of 16,501 unselected patients with breast cancer and 5890 controls by next-generation sequencing.Semantic proximity Read ↗

Germline mutations of PALB2 gene in a sequential series of Chinese patients with breast cancer.Semantic proximity Read ↗

The risk of breast cancer due to PALB2 gene mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.