Article
Clinical outcomes in women with breast cancer and a PALB2 mutation: a prospective cohort analysis.
The Lancet. Oncology - 1 Jun 2015
Cybulski Cezary, Kluźniak Wojciech, Huzarski Tomasz, Wokołorczyk Dominika, Kashyap Aniruddh, Jakubowska Anna, Szwiec Marek, Byrski Tomasz, Dębniak Tadeusz, Górski Bohdan, Sopik Victoria, Akbari Mohammad R, Sun Ping, Gronwald Jacek, Narod Steven A, Lubiński Jan
Abstract excerpt
BACKGROUND: Mutations in PALB2 predispose to breast cancer, but the effect on prognosis of carrying a PALB2 mutation has not been ascertained. We aimed to estimate the odds ratio for breast cancer in women with an inherited mutation in PALB2 and 10-year survival after breast cancer in patients who carry a PALB2 mutation. METHODS: Between 1996 and 2012, patients with invasive breast cancer were recruited...
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