Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

PALB2 mutations in breast cancer patients from a multi-ethnic region in northwest China.

European journal of medical research - 21 Oct 2015

Li Yong Tao, Jiang Wei Hua, Wang Xiao Wen, Zhang Ming Shuai, Zhang Cheng Guang, Yi Li Na, WuwaliKhan Fulati, Ayoufu Aisikaer, Ou Jiang Hua

Abstract excerpt

BACKGROUND: Germline mutations in PALB2 gene make a small contribution to heritable breast cancer susceptibility. A recent report has revealed that women with mutations in the PALB2 gene were more than nine times as likely to develop breast cancer compared to those without. The aim of this study is to understand the status of PALB2 mutations among Chinese high-risk breast cancer patients in a multi-ethnic region...

Topics

Adult
Aged
Asian People
Breast Neoplasms
China
Fanconi Anemia Complementation Group N Protein
Female
Genetic Predisposition to Disease
Humans
Middle Aged
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nuclear Proteins

Tumor Suppressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 26489409
DOI: 10.1186/s40001-015-0182-9
PMCID: PMC4618884

Genes

PALB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PALB2 mutations in breast cancer patients from a multi-ethnic region in northwest China.PMID 26489409Read ↗

Germline mutations of PALB2 gene in a sequential series of Chinese patients with breast cancer.Semantic proximity Read ↗

Spectrum of PALB2 germline mutations and characteristics of PALB2-related breast cancer: Screening of 16,501 unselected patients with breast cancer and 5890 controls by next-generation sequencing.Semantic proximity Read ↗

Spectrum and clinical relevance of PALB2 germline mutations in 7657 Chinese BRCA1/2-negative breast cancer patients.Semantic proximity Read ↗

Spectrum and characteristics of germline PALB2 pathogenic variants in 1556 early-onset breast cancer patients in China.Semantic proximity Read ↗

Common variants in the PALB2 gene confer susceptibility to breast cancer: a meta-analysis.Semantic proximity Read ↗

Five common single nucleotide polymorphisms in the PALB2 gene and susceptibility to breast cancer in eastern Chinese population.Semantic proximity Read ↗

Analysis of PALB2 mutations in 155 Japanese patients with breast and/or ovarian cancer.Semantic proximity Read ↗

Comprehensive sequencing of PALB2 in patients with breast cancer suggests PALB2 mutations explain a subset of hereditary breast cancer.Semantic proximity Read ↗

Rare germline mutations in PALB2 and breast cancer risk: a population-based study.Semantic proximity Read ↗

Association of common PALB2 polymorphisms with breast cancer risk: a case-control study.Semantic proximity Read ↗

Prevalence of PALB2 mutations in breast cancer patients in multi-ethnic Asian population in Malaysia and Singapore.Semantic proximity Read ↗

Clinical outcomes in women with breast cancer and a PALB2 mutation: a prospective cohort analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.