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Article

PALB2 and the risks for cancer: implications for clinical care.

Oncology nursing forum - 1 Jan 2015

Smith Edith C

Abstract excerpt

Mutations in the PALB2 gene are responsible for a small but significant percentage of cancer risks in familial breast and pancreatic cancer families. PALB2 mutations may be associated with an increase in other cancer risks as well. This article will provide an overview of the PALB2 gene, cancer risks associated with carrying a PALB2 mutation, and implications for patient care.

Read the complete abstract on PubMed

Topics

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Source

Identifiers

PMID: 25542327
DOI: 10.1188/15.ONF.100-102

Genes

PALB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PALB2 and the risks for cancer: implications for clinical care.PMID 25542327Read ↗

The risk of breast cancer due to PALB2 gene mutations.Semantic proximity Read ↗

Clinical outcomes in women with breast cancer and a PALB2 mutation: a prospective cohort analysis.Semantic proximity Read ↗

Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families.Semantic proximity Read ↗

Rare germline mutations in PALB2 and breast cancer risk: a population-based study.Semantic proximity Read ↗

PALB2 germline mutations in familial breast cancer cases with personal and family history of pancreatic cancerSemantic proximity Read ↗

Management of individuals with germline variants in PALB2: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG).Semantic proximity Read ↗

PALB2: research reaching to clinical outcomes for women with breast cancerSemantic proximity Read ↗

PALB2 mutations in familial breast and pancreatic cancer.Semantic proximity Read ↗

Common variants in the PALB2 gene confer susceptibility to breast cancer: a meta-analysis.Semantic proximity Read ↗

Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene.Semantic proximity Read ↗

Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer.Semantic proximity Read ↗

Meta-analysis of breast cancer risk for individuals with PALB2 pathogenic variants.Semantic proximity Read ↗

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