Article
Squamous cell carcinoma initially occurring on the tongue dorsum: a case series report with molecular analysis.
Diagnostic pathology - 22 Apr 2024
Ono Sawako, Hirose Katsutoshi, Sukegawa Shintaro, Obata Kyoichi, Masui Masanori, Hasegawa Kazuaki, Fujimura Ai, Shimada Katsumitsu, Nakamura Satoko, Teramoto Akari, Hori Yumiko, Morii Eiichi, Motooka Daisuke, Igawa Takuro, Tanaka Takehiro, Nagatsuka Hitoshi, Toyosawa Satoru, Yamamoto Hidetaka
Abstract excerpt
BACKGROUND: Squamous cell carcinoma (SCC) of the dorsum of the tongue is extremely rare, and it clinically resembles various benign lesions. Somatic mutations in TP53 and some driver genes were implicated in the development of SCC; however, the somatic genetic characteristics of dorsal tongue SCC remain unknown. With a detailed analysis of gene mutations in dorsal tongue SCC, we aimed to better understand its...
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