Article
Establishment and characterization of an oral tongue squamous cell carcinoma cell line from a never-smoking patient.
Oral oncology - 1 Jun 2017
Wang Steven J, Asthana Saurabh, van Zante Annemieke, Heaton Chase M, Phuchareon Janyaporn, Stein Leighton, Higuchi Saito, Kishimoto Tomoya, Chiu Charles Y, Olshen Adam B, McCormick Frank, Tetsu Osamu
Abstract excerpt
OBJECTIVE: The rising incidence of oral tongue squamous cell carcinoma (OTSCC) in patients who have never smoked and the paucity of knowledge of its biological behavior prompted us to develop a new cell line originating from a never-smoker. MATERIALS AND METHODS: Fresh tumor tissue of keratinizing OTSCC was collected from a 44-year-old woman who had never smoked. Serum-free media with a low calcium concentration...
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